SrasV1, Main, Exploration, bibRecord, 003524

A Live Attenuated Severe Acute Respiratory Syndrome Coronavirus Is Immunogenic and Efficacious in Golden Syrian Hamsters

Identifieur interne : 003524 ( Main/Exploration ); précédent : 003523; suivant : 003525

A Live Attenuated Severe Acute Respiratory Syndrome Coronavirus Is Immunogenic and Efficacious in Golden Syrian Hamsters

Auteurs : Elaine W. Lamirande [États-Unis] ; Marta L. Dediego [Espagne] ; Anjeanette Roberts [États-Unis] ; Jadon P. Jackson [États-Unis] ; Enrique Alvarez [Espagne] ; Tim Sheahan [États-Unis] ; Wun-Ju Shieh [États-Unis] ; Sherif R. Zaki [États-Unis] ; Ralph Baric [États-Unis] ; Luis Enjuanes [Espagne] ; Kanta Subbarao [États-Unis]

Source :

Journal of virology [ 0022-538X ] ; 2008.

RBID : Pascal:08-0363001

Descripteurs français

Pascal (Inist)
- Coronavirus, Hamster, Souche atténuée, Immunogénicité, Animal, Virologie, Syndrome respiratoire aigu sévère.

English descriptors

KwdEn :
- Animal, Attenuated strain, Coronavirus, Hamster, Immunogenicity, Severe acute respiratory syndrome, Virology.

Abstract

The immunogenicity and protective efficacy of a live attenuated vaccine consisting of a recombinant severe acute respiratory syndrome (SARS) coronavirus lacking the E gene (rSARS-CoV-AE) were studied using hamsters. Hamsters immunized with rSARS-CoV-AE developed high serum-neutralizing antibody titers and were protected from replication of homologous (SARS-CoV Urbani) and heterologous (GD03) SARS-CoV in the upper and lower respiratory tract. rSARS-CoV-AE-immunized hamsters remained active following wild-type virus challenge, while mock-immunized hamsters displayed decreased activity. Despite being attenuated in replication in the respiratory tract, rSARS-CoV-AE is an immunogenic and efficacious vaccine in hamsters.

Affiliations:

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 000263
to stream PascalFrancis, to step Curation: 000725
to stream PascalFrancis, to step Checkpoint: 000304
to stream Main, to step Merge: 003630
to stream Main, to step Curation: 003524

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">A Live Attenuated Severe Acute Respiratory Syndrome Coronavirus Is Immunogenic and Efficacious in Golden Syrian Hamsters</title>
<author><name sortKey="Lamirande, Elaine W" sort="Lamirande, Elaine W" uniqKey="Lamirande E" first="Elaine W." last="Lamirande">Elaine W. Lamirande</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratory of Infectious Diseases, NIAID, NIH</s1>
<s2>Bethesda, Maryland 20892</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Bethesda, Maryland 20892</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Dediego, Marta L" sort="Dediego, Marta L" uniqKey="Dediego M" first="Marta L." last="Dediego">Marta L. Dediego</name>
<affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Molecular and Cell Biology, Centro Nacional de Biotecnologia (CNB), Nacional de Biotecnologia (CSIC), Campus Universidad Autónoma, Darwin 3, Cantoblanco</s1>
<s2>28049 Madrid</s2>
<s3>ESP</s3>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
<placeName><region nuts="2" type="communauté">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Roberts, Anjeanette" sort="Roberts, Anjeanette" uniqKey="Roberts A" first="Anjeanette" last="Roberts">Anjeanette Roberts</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratory of Infectious Diseases, NIAID, NIH</s1>
<s2>Bethesda, Maryland 20892</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Bethesda, Maryland 20892</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jackson, Jadon P" sort="Jackson, Jadon P" uniqKey="Jackson J" first="Jadon P." last="Jackson">Jadon P. Jackson</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratory of Infectious Diseases, NIAID, NIH</s1>
<s2>Bethesda, Maryland 20892</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Bethesda, Maryland 20892</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Alvarez, Enrique" sort="Alvarez, Enrique" uniqKey="Alvarez E" first="Enrique" last="Alvarez">Enrique Alvarez</name>
<affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Molecular and Cell Biology, Centro Nacional de Biotecnologia (CNB), Nacional de Biotecnologia (CSIC), Campus Universidad Autónoma, Darwin 3, Cantoblanco</s1>
<s2>28049 Madrid</s2>
<s3>ESP</s3>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
<placeName><region nuts="2" type="communauté">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sheahan, Tim" sort="Sheahan, Tim" uniqKey="Sheahan T" first="Tim" last="Sheahan">Tim Sheahan</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Epidemiology, University of North Carolina</s1>
<s2>Chapel Hill, North Carolina 27599</s2>
<s3>USA</s3>
<sZ>6 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Chapel Hill, North Carolina 27599</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shieh, Wun Ju" sort="Shieh, Wun Ju" uniqKey="Shieh W" first="Wun-Ju" last="Shieh">Wun-Ju Shieh</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Infectious Diseases Pathology Activity, Centers for Disease Control and Prevention</s1>
<s2>Atlanta, Georgia 30333</s2>
<s3>USA</s3>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Atlanta, Georgia 30333</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zaki, Sherif R" sort="Zaki, Sherif R" uniqKey="Zaki S" first="Sherif R." last="Zaki">Sherif R. Zaki</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Infectious Diseases Pathology Activity, Centers for Disease Control and Prevention</s1>
<s2>Atlanta, Georgia 30333</s2>
<s3>USA</s3>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Atlanta, Georgia 30333</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Baric, Ralph" sort="Baric, Ralph" uniqKey="Baric R" first="Ralph" last="Baric">Ralph Baric</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Epidemiology, University of North Carolina</s1>
<s2>Chapel Hill, North Carolina 27599</s2>
<s3>USA</s3>
<sZ>6 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Chapel Hill, North Carolina 27599</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Enjuanes, Luis" sort="Enjuanes, Luis" uniqKey="Enjuanes L" first="Luis" last="Enjuanes">Luis Enjuanes</name>
<affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Molecular and Cell Biology, Centro Nacional de Biotecnologia (CNB), Nacional de Biotecnologia (CSIC), Campus Universidad Autónoma, Darwin 3, Cantoblanco</s1>
<s2>28049 Madrid</s2>
<s3>ESP</s3>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
<placeName><region nuts="2" type="communauté">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Subbarao, Kanta" sort="Subbarao, Kanta" uniqKey="Subbarao K" first="Kanta" last="Subbarao">Kanta Subbarao</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratory of Infectious Diseases, NIAID, NIH</s1>
<s2>Bethesda, Maryland 20892</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Bethesda, Maryland 20892</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">08-0363001</idno>
<date when="2008">2008</date>
<idno type="stanalyst">PASCAL 08-0363001 INIST</idno>
<idno type="RBID">Pascal:08-0363001</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000263</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000725</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000304</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000304</idno>
<idno type="wicri:doubleKey">0022-538X:2008:Lamirande E:a:live:attenuated</idno>
<idno type="wicri:Area/Main/Merge">003630</idno>
<idno type="wicri:Area/Main/Curation">003524</idno>
<idno type="wicri:Area/Main/Exploration">003524</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">A Live Attenuated Severe Acute Respiratory Syndrome Coronavirus Is Immunogenic and Efficacious in Golden Syrian Hamsters</title>
<author><name sortKey="Lamirande, Elaine W" sort="Lamirande, Elaine W" uniqKey="Lamirande E" first="Elaine W." last="Lamirande">Elaine W. Lamirande</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratory of Infectious Diseases, NIAID, NIH</s1>
<s2>Bethesda, Maryland 20892</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Bethesda, Maryland 20892</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Dediego, Marta L" sort="Dediego, Marta L" uniqKey="Dediego M" first="Marta L." last="Dediego">Marta L. Dediego</name>
<affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Molecular and Cell Biology, Centro Nacional de Biotecnologia (CNB), Nacional de Biotecnologia (CSIC), Campus Universidad Autónoma, Darwin 3, Cantoblanco</s1>
<s2>28049 Madrid</s2>
<s3>ESP</s3>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
<placeName><region nuts="2" type="communauté">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Roberts, Anjeanette" sort="Roberts, Anjeanette" uniqKey="Roberts A" first="Anjeanette" last="Roberts">Anjeanette Roberts</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratory of Infectious Diseases, NIAID, NIH</s1>
<s2>Bethesda, Maryland 20892</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Bethesda, Maryland 20892</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jackson, Jadon P" sort="Jackson, Jadon P" uniqKey="Jackson J" first="Jadon P." last="Jackson">Jadon P. Jackson</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratory of Infectious Diseases, NIAID, NIH</s1>
<s2>Bethesda, Maryland 20892</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Bethesda, Maryland 20892</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Alvarez, Enrique" sort="Alvarez, Enrique" uniqKey="Alvarez E" first="Enrique" last="Alvarez">Enrique Alvarez</name>
<affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Molecular and Cell Biology, Centro Nacional de Biotecnologia (CNB), Nacional de Biotecnologia (CSIC), Campus Universidad Autónoma, Darwin 3, Cantoblanco</s1>
<s2>28049 Madrid</s2>
<s3>ESP</s3>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
<placeName><region nuts="2" type="communauté">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sheahan, Tim" sort="Sheahan, Tim" uniqKey="Sheahan T" first="Tim" last="Sheahan">Tim Sheahan</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Epidemiology, University of North Carolina</s1>
<s2>Chapel Hill, North Carolina 27599</s2>
<s3>USA</s3>
<sZ>6 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Chapel Hill, North Carolina 27599</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shieh, Wun Ju" sort="Shieh, Wun Ju" uniqKey="Shieh W" first="Wun-Ju" last="Shieh">Wun-Ju Shieh</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Infectious Diseases Pathology Activity, Centers for Disease Control and Prevention</s1>
<s2>Atlanta, Georgia 30333</s2>
<s3>USA</s3>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Atlanta, Georgia 30333</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zaki, Sherif R" sort="Zaki, Sherif R" uniqKey="Zaki S" first="Sherif R." last="Zaki">Sherif R. Zaki</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Infectious Diseases Pathology Activity, Centers for Disease Control and Prevention</s1>
<s2>Atlanta, Georgia 30333</s2>
<s3>USA</s3>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Atlanta, Georgia 30333</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Baric, Ralph" sort="Baric, Ralph" uniqKey="Baric R" first="Ralph" last="Baric">Ralph Baric</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Epidemiology, University of North Carolina</s1>
<s2>Chapel Hill, North Carolina 27599</s2>
<s3>USA</s3>
<sZ>6 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Chapel Hill, North Carolina 27599</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Enjuanes, Luis" sort="Enjuanes, Luis" uniqKey="Enjuanes L" first="Luis" last="Enjuanes">Luis Enjuanes</name>
<affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Molecular and Cell Biology, Centro Nacional de Biotecnologia (CNB), Nacional de Biotecnologia (CSIC), Campus Universidad Autónoma, Darwin 3, Cantoblanco</s1>
<s2>28049 Madrid</s2>
<s3>ESP</s3>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
<placeName><region nuts="2" type="communauté">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Subbarao, Kanta" sort="Subbarao, Kanta" uniqKey="Subbarao K" first="Kanta" last="Subbarao">Kanta Subbarao</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratory of Infectious Diseases, NIAID, NIH</s1>
<s2>Bethesda, Maryland 20892</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Bethesda, Maryland 20892</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Journal of virology</title>
<title level="j" type="abbreviated">J. virol.</title>
<idno type="ISSN">0022-538X</idno>
<imprint><date when="2008">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Journal of virology</title>
<title level="j" type="abbreviated">J. virol.</title>
<idno type="ISSN">0022-538X</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animal</term>
<term>Attenuated strain</term>
<term>Coronavirus</term>
<term>Hamster</term>
<term>Immunogenicity</term>
<term>Severe acute respiratory syndrome</term>
<term>Virology</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Coronavirus</term>
<term>Hamster</term>
<term>Souche atténuée</term>
<term>Immunogénicité</term>
<term>Animal</term>
<term>Virologie</term>
<term>Syndrome respiratoire aigu sévère</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The immunogenicity and protective efficacy of a live attenuated vaccine consisting of a recombinant severe acute respiratory syndrome (SARS) coronavirus lacking the E gene (rSARS-CoV-AE) were studied using hamsters. Hamsters immunized with rSARS-CoV-AE developed high serum-neutralizing antibody titers and were protected from replication of homologous (SARS-CoV Urbani) and heterologous (GD03) SARS-CoV in the upper and lower respiratory tract. rSARS-CoV-AE-immunized hamsters remained active following wild-type virus challenge, while mock-immunized hamsters displayed decreased activity. Despite being attenuated in replication in the respiratory tract, rSARS-CoV-AE is an immunogenic and efficacious vaccine in hamsters.</div>
</front>
</TEI>
<affiliations><list><country><li>Espagne</li>
<li>États-Unis</li>
</country>
<region><li>Communauté de Madrid</li>
</region>
</list>
<tree><country name="États-Unis"><noRegion><name sortKey="Lamirande, Elaine W" sort="Lamirande, Elaine W" uniqKey="Lamirande E" first="Elaine W." last="Lamirande">Elaine W. Lamirande</name>
</noRegion>
<name sortKey="Baric, Ralph" sort="Baric, Ralph" uniqKey="Baric R" first="Ralph" last="Baric">Ralph Baric</name>
<name sortKey="Jackson, Jadon P" sort="Jackson, Jadon P" uniqKey="Jackson J" first="Jadon P." last="Jackson">Jadon P. Jackson</name>
<name sortKey="Roberts, Anjeanette" sort="Roberts, Anjeanette" uniqKey="Roberts A" first="Anjeanette" last="Roberts">Anjeanette Roberts</name>
<name sortKey="Sheahan, Tim" sort="Sheahan, Tim" uniqKey="Sheahan T" first="Tim" last="Sheahan">Tim Sheahan</name>
<name sortKey="Shieh, Wun Ju" sort="Shieh, Wun Ju" uniqKey="Shieh W" first="Wun-Ju" last="Shieh">Wun-Ju Shieh</name>
<name sortKey="Subbarao, Kanta" sort="Subbarao, Kanta" uniqKey="Subbarao K" first="Kanta" last="Subbarao">Kanta Subbarao</name>
<name sortKey="Zaki, Sherif R" sort="Zaki, Sherif R" uniqKey="Zaki S" first="Sherif R." last="Zaki">Sherif R. Zaki</name>
</country>
<country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Dediego, Marta L" sort="Dediego, Marta L" uniqKey="Dediego M" first="Marta L." last="Dediego">Marta L. Dediego</name>
</region>
<name sortKey="Alvarez, Enrique" sort="Alvarez, Enrique" uniqKey="Alvarez E" first="Enrique" last="Alvarez">Enrique Alvarez</name>
<name sortKey="Enjuanes, Luis" sort="Enjuanes, Luis" uniqKey="Enjuanes L" first="Luis" last="Enjuanes">Luis Enjuanes</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003524 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003524 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    SrasV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Pascal:08-0363001
   |texte=   A Live Attenuated Severe Acute Respiratory Syndrome Coronavirus Is Immunogenic and Efficacious in Golden Syrian Hamsters
}}

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 28 14:49:16 2020. Site generation: Sat Mar 27 22:06:49 2021

	Serveur d'exploration SRAS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration SRAS

A Live Attenuated Severe Acute Respiratory Syndrome Coronavirus Is Immunogenic and Efficacious in Golden Syrian Hamsters

A Live Attenuated Severe Acute Respiratory Syndrome Coronavirus Is Immunogenic and Efficacious in Golden Syrian Hamsters

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri